Dementia is a clinical syndrome with a number of different causes. It is characterised by deterioration in cognitive, behavioural, social and emotional functioning. Pharmacological interventions are available but have limited effect on many of the syndrome’s features. However, receptivity to Read more…
The World Happiness Report is more a study of life satisfaction than smiles and laughter. It is based on a survey by Gallup, where participants are asked to rate their lives out of ten. Finland (7.7) and Scandinavian countries were Read more…
In simple terms, an AI agent is a system that can perceive its environment, make decisions, and take actions to achieve specific goals—often with minimal human involvement. Think of it as a kind of digital assistant that can learn, reason, Read more…
Glucagon-Like Peptide-1 (GLP-1) is a natural hormone secreted by the intestinal – L cells in response to food that enhances insulin secretion, suppresses glucagon rerelease, delays gastric emptying, acts on the brain to promote satiety. GLP-1 plays a vital role Read more…
BACKGROUND Generative artificial intelligence (Gen-AI) chatbots hold promise for building highly personalized, effective mental health treatments at scale, while also addressing user engagement and retention issues common among digital therapeutics. METHODS A RCT with (N=210) with clinically significant symptoms of Read more…
American Gastroenterological Association (AGA) guidelines are the first to make priority recommendations for antiobesity medication selection on the basis of available evidence from individual agent trials explicitly recommending the use of (a) semaglutide 2.4 mg because of the magnitude of Read more…
International guidelines support the use of diet based interventions as front line therapy from increased soluble fiber to more general dietary changes (eg, NICE guidance, low-FODMAP diet). Guidelines overall support psychological and behavior based interventions with caveats to patient selection Read more…
Antidepressants are commonly used to treat low back pain and spine‐related leg pain. However, their benefits and harms are uncertain. The Cochrane review included 26 randomised controlled trials. Eighteen studies included 2535 participants with non‐specific low back pain, seven studies Read more…
*The picture is from YG2D.COM ‘Being Mortal: Medicine and what matters in the end’ is a new book by the best-selling US surgeon and author Atul Gwande. Death, dying or being mortal is not a favourite topic of doctors. Although this book Read more…
Omega-3 fatty acids have been used in the treatment and prevention of coronary artery disease, although current evidence suggests they may be of limited benefit. Peripheral arterial disease and coronary artery disease share a similar pathogenesis The Cochrane Review had Read more…
