This is a question that most of may have asked ourselves at some point in our lives. I am reading a book by the same name. The majority of us may think that we have to be the best and compare themselves and others against impossibly high standards resulting in Read more
Dementia is a clinical syndrome with a number of different causes. It is characterised by deterioration in cognitive, behavioural, social and emotional functioning. Pharmacological interventions are available but have limited effect on many of the syndrome’s features. However, receptivity to music may remain until the late phases of dementia, and Read more
The World Happiness Report is more a study of life satisfaction than smiles and laughter. It is based on a survey by Gallup, where participants are asked to rate their lives out of ten. Finland (7.7) and Scandinavian countries were ranked in the top positions. The global average was 5.6 Read more
In simple terms, an AI agent is a system that can perceive its environment, make decisions, and take actions to achieve specific goals—often with minimal human involvement. Think of it as a kind of digital assistant that can learn, reason, and act on your behalf within a defined task or Read more
Glucagon-Like Peptide-1 (GLP-1) is a natural hormone secreted by the intestinal – L cells in response to food that enhances insulin secretion, suppresses glucagon rerelease, delays gastric emptying, acts on the brain to promote satiety. GLP-1 plays a vital role in blood sugar control. It has been reported that GLP-1 Read more
BACKGROUND Generative artificial intelligence (Gen-AI) chatbots hold promise for building highly personalized, effective mental health treatments at scale, while also addressing user engagement and retention issues common among digital therapeutics. METHODS A RCT with (N=210) with clinically significant symptoms of major depressive disorder (MDD), generalized anxiety disorder (GAD), or at Read more
American Gastroenterological Association (AGA) guidelines are the first to make priority recommendations for antiobesity medication selection on the basis of available evidence from individual agent trials explicitly recommending the use of (a) semaglutide 2.4 mg because of the magnitude of clinical benefit (b) next prioritize liraglutide 3.0 mg, followed by Read more
International guidelines support the use of diet based interventions as front line therapy from increased soluble fiber to more general dietary changes (eg, NICE guidance, low-FODMAP diet). Guidelines overall support psychological and behavior based interventions with caveats to patient selection and differing suggestions for where these should be positioned. Complementary Read more
Antidepressants are commonly used to treat low back pain and spine‐related leg pain. However, their benefits and harms are uncertain. The Cochrane review included 26 randomised controlled trials. Eighteen studies included 2535 participants with non‐specific low back pain, seven studies included 329 participants with spine‐related leg pain, and one study Read more
*The picture is from YG2D.COM ‘Being Mortal: Medicine and what matters in the end’ is a new book by the best-selling US surgeon and author Atul Gwande. Death, dying or being mortal is not a favourite topic of doctors. Although this book will not change your whole life, it could very well Read more