Gene editing and Designer ‘CRISPR’ babies

Gene editing and Designer ‘CRISPR’ babies

  Gene editing or genome editing is the technique used to replace or cutting pieces of DNA [Ref]. Using a component known as  CRISPR to precisely pinpoint the sequence of DNA in the gene, an enzyme called Cas9 is used to cut through the part identified. It can also replace a removed part by another sequence of DNA. This technique can be used to replace a faculty gene or change a gene to make it behave differently. Gene editing can have very good effects like altering a disease gene or modifying a diseased gene to behave normally. However gene editing

New Cholesterol Guidelines Personalize Risk and Add Treatments – JAMA 2019 Feb 6

New Cholesterol Guidelines Personalize Risk and Add Treatments – JAMA 2019 Feb 6

In the new guidelines, statin treatment targets are back for both primary and secondary prevention. Patients whose 10-year risk of ASCVD is 20% or more should try to reduce LDL-C levels by at least 50%, the same goal as for people with clinical ASCVD. Those with more intermediate risk should aim for at least a 30% decrease. The new update was met with considerably less controversy than the last incarnation, which deemphasized LDL-C treatment targets and introduced the AHA/ACC ASCVD risk calculator. The updated guidelines and a companion AHA/ACC special report on risk assessment tools acknowledge that the calculator estimates risk for an average